Gallbladder cancer with ascites in a child with metachromatic leukodystrophy

Acetobacter indonesiensis Bacteremia in Child with Metachromatic Leukodystrophy

from cats, belonged to ST93 and a new ST strain, respectively. Isolates EC08 and EC09, from the patients who shared the same hospital room with the pet shop worker, were ST156 (Table). Results of pulsed-field gel electro-phoresis were consistent with multilocus sequence typing results and showed that isolates consisted of 5 typeslate EC07 was clonally related to 4 E. coli strains from dogs, acc...

Juvenile metachromatic leukodystrophy in a boy with epilepsy.

M leukodystrophy (MLD) is an autosomal recessive disorder, caused by deficiency of arylsulfatase A (cerebroside sulfatase A, ASA), which results in accumulation of sulfatides, mainly in the brain and peripheral nerves. The estimated frequency of MLD from previous reports is 1 in 40,000 cases. The deficiency in ASA activity is caused by mutations in the ASA gene. The deficiency is systemic and a...

Sulfatide levels correlate with severity of neuropathy in metachromatic leukodystrophy

OBJECTIVE Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disorder due to deficient activity of arylsulfatase A (ASA) that causes accumulation of sulfatide and lysosulfatide. The disorder is associated with demyelination and axonal loss in the central and peripheral nervous systems. The late infantile form has an early-onset, rapidly progressive course with severe...

Metachromatic leukodystrophy: two sides of a coin.

Human urinary sulfatides in patients with sulfatidosis (metachromatic leukodystrophy).

The excretion of sulfatides in human urine was studied. 24-hr urine collections were filtered. Urinary glycolipids were extracted from the filter paper and fractionated on diethylaminoethyl cellulose and silicic acid columns, and by thin-layer chromatography. Fatty acids and long-chain bases were analyzed by gas-liquid chromatography of the corresponding esters and aldehydes. Glycosyl ceramide ...